一本道无码

A 一本道无码-led team of researchers from the Advanced Research Projects Agency for Health (ARPA-H).听The funds will fast track a bioelectronic implant that could radically improve treatment options and significantly reduce the cost of care for patients with obesity and Type 2 diabetes.

The award will drive the accelerated development and testing of 鈥淩x On-site Generation Using Electronics (ROGUE),鈥� a bioelectrical device that hosts a 鈥渓iving pharmacy,鈥� consisting of engineered cells that produce biological therapy to treat Type 2 diabetes and obesity. The device will offer continuous, adjustable and low-cost therapy deployment via a minimally invasive procedure performed in an outpatient clinic. Additionally, in a stark contrast from the traditional delivery of biologics, it will eliminate the need for weekly injections, trips to the pharmacy and careful storage of expensive medications.

鈥淭his project is the peak deployment of several core technologies we have developed and refined over the past five years, as part of the Bioelectric Medicine Initiative at 一本道无码,鈥� said 一本道无码 materials science and bioengineer Tzahi Cohen-Karni,(opens in new window) who serves as primary investigator on the ARPA-H award. 鈥淏ioelectronic devices offer a myriad of benefits, including adjustable therapy delivery, dynamic monitoring and reduced biologics health care costs. We are leveraging our collective strengths to develop an effective and sustainable solution to reduce the burden of chronic care for two global epidemics 鈥� obesity and Type 2 diabetes.鈥�

ARPA-H is a federal funding agency听 to support research that has 鈥渢he potential to transform entire areas of medicine and health.鈥澨�

The collaborative team includes 17听co-principal investigators from Boston University, Georgia Institute of Technology, Northwestern University, Rice University, the University of California, Berekely, the Mayo Clinic and New York City-based Bruder Consulting and Venture Group. It includes engineers, physicians and multidisciplinary specialists in synthetic biology, materials science, electrical engineering and other fields.听

鈥� is determined to facilitate the clinical translation and commercialization of this breakthrough and market disruptive, first-in-class technology,鈥� said Rice University bioengineer Omid Veiseh, co-investigator on the ARPA-H award. 鈥淲e are developing a minimally invasive implant that can produce a year鈥檚 supply of a treatment for chronic diseases like Type 2 diabetes and obesity. With a simple, once-a-year procedure, ROGUE will replace current treatments that have to be administered daily, weekly or monthly.鈥�

This effort is funded under and includes funding for a first-in-human clinical trial for patients facing obesity and Type 2 diabetes. The trial preparation is slated to begin in the fifth year of the six-year project.

This project is supported by the听.听Additional researchers on the project include Carnegie Mellon faculty members Adam Feinberg, Charlie Ren, Phil Campbell, and Subha Das.